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. Author manuscript; available in PMC: 2008 Aug 1.
Published in final edited form as: Bone. 2007 Apr 20;41(2):282–289. doi: 10.1016/j.bone.2007.04.175

Table 1.

Cynomolgus macaques; prevalence and cross-sectional area of periarticular osteophytes by treatment group.

OVX
SPE
ERT
TOTAL
prevalence (%) area (mm2) prevalence (%) area (mm2) prevalence (%) area (mm2) prevalence (%)
Abaxial Lateral 46/54 (85.2%) 0.67 ± 0.39 51/57 (89.5%) 0.78 ± 0.48 36/54 (66.7%)a 0.87 ± 0.68 133/165 (80.6%)
Abaxial Medial 39/54 (72.2%) 0.38 ± 0.33 40/57 (70.2%) 0.49 ± 0.41 29/54 (53.7%) 0.41 ± 0.35 108/165 (65.5%)
Axial Lateral Method A 19/52 (36.5%) 0.64 ± 0.41 26/53 (49.1%) 0.59 ± 0.32 22/53 (41.5%) 0.54 ± 0.21 67/158 (42.4%)
Axial Medial Method A 7/52 (13.5%) 1.00 ± 0.67 7/53 (13.2%) 1.02 ± 0.32 5/53 (9.4%) 1.34 ± 0.49 19/158 (12.0%)
Axial Lateral Method B 19/52 (36.5%) 0.64 ± 0.41 26/53 (49.1%) 0.59 ± 0.32 22/53 (41.5%) 0.54 ± 0.21 67/158 (42.4%)
Axial Medial Method B 39/52 (75.0%) 1.08 ± 0.47 37/53 (69.8%) 1.16 ± 0.38 43/53 (81.1%) 1.20 ± 0.54 119/158 (75.3%)

Prevalence data expressed as the number of subjects with osteophytes present/number of subjects in each treatment group (%).

Area data expressed as mean values ± standard deviation.

a

denotes a significant difference between SPE and ERT treatment groups (p<0.01).

None of the area comparisons were statistically significant across treament groups (Kruskal-Wallis test).

OVX = ovariectomized control group; SPE = soy phytoestrogen group; ERT = estrogen replacement group.