Table I.
IRM measurements at 1 T of neuroferritinopathy samples
| Patient - Fraction | IRMsat,50K, μemu/g(WT) | [MagnBl], ng/g(WT) | [MagnSPM], ng/g(WT) | [Ferritin], μg/g(WT) | [Ferritin]/[MagnSPM] | ||
|---|---|---|---|---|---|---|---|
| 50K | 150K | 300K | |||||
| 1-1 | 6.3* | 1.9 | - | 128[4]* | 96[9]* | 286[7]* | 2.98* |
| 1-2 | - | 2.8 | - | 57[3] | - | - | - |
| 1-3 | - | 3.4 | - | 69[17] | - | - | - |
| 2-1 | 5.0* | 2.6 | - | 102[4]* | 44[14]* | 132[6]* | 3.00* |
| 2-2 | - | 6.1 | - | 124[21] | - | - | - |
|
| |||||||
| - | - | 0.6 | 12 | - | - | - | |
| Controls | - | - | 0.6 | 12 | - | - | - |
| - | - | 1.3 | 27 | - | - | - | |
*
numbers based on an empirical fit of an IRM curve rather than a measurement at saturation. The error is based on an instrumental error for single point measurements and on the variance of the refined parameter for sample 1-1 and 2-1.