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. Author manuscript; available in PMC: 2007 Sep 24.
Published in final edited form as: Cell Motil Cytoskeleton. 2005 May;61(1):34–48. doi: 10.1002/cm.20063

Figure 8.

Figure 8

FRAP recovery rates of two cypher skeletal muscle isoforms and their domains in the Z-bands of mature myofibrils. (A) The schematic diagrams of cypher-1s and cypher-2s indicates the shared PDZ domain (amino acids 1-84) present in both isoforms, and the three LIM domains (amino acids 404–472) present only in cypher-1s. (B) The average FRAP recovery curves of cypher-1s (black rectangles), cypher-2s (black circles), cypher-LIM domains (white circles) and cypher-PDZ domain (cross) in the Z-bands of mature myofibrils. The C-terminal region of cypher-2s decreases the dynamics of the cypher-2S PDZ domain, while cypher-1s amino acids 1-364 increase the dynamics of the LIM domains. (C) Comparison of the fast and slow mobile fractions of the cyphers, as well as their LIM and PDZ domains in the Z-bands of mature myofibrils. Values are the means ± SDs.