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Effect of fastuosain and bromelain treatment on B16F10-Nex2 cell invasion of Matrigel in vitro. Treatment with fastuosain or bromelain (10 µg/ml, 1 hour) inhibited B16F10-Nex2 cell invasion. Incubation with anti-CD44 mAbs promotes a similar inhibition of the cell invasion process. The effect is expressed as percentages relative to controls (invasion by cells treated with saline). Standard deviations from the means of three experiments are shown.
