Figure 3.
Effects of the mutations on other aspects of OR regulation. Response of PRM.lacZ reporters (A) and PR.lacZ reporters (B,C) to CI (A,C), or Cro (B) supplied by IPTG-inducible plasmids. The λ fragment extends from the +62 of PRM to the +43 of PR. The inset in C shows reporter expression with CI supplied from a λatt80 prophage. (D) Translational fusion reporters showing the effect of the OR mutations on cI translation from PRE mRNA. λ PRE is substituted by the constitutive 186 pB promoter. (A–D) Error bars and ranges are 95% confidence limits.