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. Author manuscript; available in PMC: 2007 Sep 25.
Published in final edited form as: J Immunol. 2006 Jul 1;177(1):169–176. doi: 10.4049/jimmunol.177.1.169

FIGURE 5.

FIGURE 5

Leptin prevents LPS-induced acute thymic atrophy in BALB/c mice. Female BALB/c mice were simultaneously administered (i.p.) either saline or leptin (1 μg/g body weight) and challenged with either saline or E. coli LPS (100 μg/mouse). Ten mice per group were euthanized on days 1, 7, and 14 to monitor the effect of leptin on LPS-induced acute thymic atrophy. Mean thymus weight ± SEM was determined at each harvest time as an indicator of thymic atrophy. *, p ≤ 0.05 compared with saline-treated controls.