. Author manuscript; available in PMC: 2007 Sep 25.

Published in final edited form as: J Immunol. 2006 Jul 1;177(1):169–176. doi: 10.4049/jimmunol.177.1.169

Table IV.

Six-hour serum cytokine levels post LPS treatment ± a single dose of leptin

Cytokine	Saline^a	Leptin^a	LPS^a	LPS +Leptin^a	Percent Change LPS vs LPS + Leptin (%)	p Value
IL-1α	63 ± 26	48 ± 27	505 ± 59	395 ± 113	−22	0.0147
IL-1β	29 ± 6	20 ± 7	458 ± 107	322 ± 68	−30	0.0032
IL-2	4 ± 0.3	2 ± 2	32 ± 6	22 ± 4	−31	0.0003
IL-4	0.2 ± 0.1	0.1 ± 0.1	4 ± 0.4	2 ± 0.4	−39	0.0000
IL-5	9 ± 3	19 ± 15	55 ± 25	29 ± 10	−47	0.0001
IL-6	8 ± 7	0.4 ± 0.9	3658 ± 841	1505 ± 283	−59	0.0000
IL-12 p70	43 ± 28	31 ± 37	653 ± 175	320 ± 83	−51	0.0011
IL-17	7 ± 2	9 ± 9	53 ± 17	37 ± 13	−30	0.0001
GM-CSF	6 ± 6	5 ± 2	97 ± 10	83 ± 9	−14	0.0042
IFN-γ	33 ± 30	10 ± 11	186.7 ± 38	159 ± 19	−15	0.0702

Mean ± SD cytokine level in serum (picograms per milliliter), n = 10 mice/group.