Table 1.
Various lipoprotein lipids (mean ± 1 standard deviation) at baseline and after 4-week, 12-week, and 24-week treatment with lovastatin and niacin combination
| Parameter (mg/dL) | Baseline (n = 131) | Week 4 (n = 120) | Week 12 (n = 115) | Week 24 (n = 114) |
|---|---|---|---|---|
| Total cholesterol | 233.9 ± 27.4 | 206.3 ± 27.4* | 189.8 ± 31.3* | 174.9 ± 27.2* |
| Triglycerides | 171.1 ± 72.2 | 159.5 ± 75.0* | 149.2 ± 45.0* | 135.2 ± 40.5* |
| HDL cholesterol | 45.6 ± 7.4 | 48.9 ± 7.4* | 51.6 ± 8.7* | 53.9 ± 9.5* |
| LDL cholesterol | 153.4 ± 21.9 | 127.3 ± 20.8* | 109.2 ± 26.8* | 95.1 ± 23.1* |
| ApoA1/B | 0.96 ± 0.67 | 1.04 ± 0.42* | 1.17 ± 0.49* | 1.45 ± 0.51* |
| Lipoprotein (a) | 48.5 ± 26.4 | 40.1 ± 21.2* | 35.4 ± 20.6* | 26.9 ± 19.2* |
*
p < 0.05.
Abbreviations: HDL, high density lipoprotein cholesterol; LDL, low density lipoprotein cholesterol; Apo, apolipoprotein.