Table 2.
Prognostic value of CRP in acute coronary syndromes
| Study | n | Endpoint | Cutoff | Risk estimates |
|---|---|---|---|---|
| Short term | ||||
| Liuzzo et al 1994 | 31 | Death/MI/urg. revasc | 3.0 mg/L | RR=2.6 |
| Morrow et al 1998 | 437 | Death | 15.5 mg/L | RR=16.1 |
| Rebuzzi et al 1998 | 102 | MI | 3 mg/L | RR=6.0 |
| Verheggen et al 1999 | 211 | Refractory angina | 6 mg/L | OR=2.19 |
| Oltrona et al 1997 | 140 | Death/MI/revasc | 10 mg/L | p=ns |
| Montalescot et al 1998 | 68 | Death/MI/angina/revasc | 5 mg/L | p=ns |
| Mid term | ||||
| Ridker et al 2005 | 3,745 | Death/MI | 2 mg/L | RR=1.4 |
| Muller et al 2002 | 1,042 | Death | 10 mg/L | OR=4.1 |
| Heeschen et al 2000 | 447 | Death/MI | 10 mg/L | RR=2.0 |
| Lindhal et al 2000 | 917 | Death | 10 mg/L | RR=2.6 |
| Ferreiros et al 1999 | 194 | Death/MI/refractory angina | 15 mg/L | HR=3.16 |
| Biasucci et al 1999 | 53 | UA | 3 mg/L | OR=8.6 |
| Toss et al 1997 | 965 | Death/MI | >10 mg/L vs <2.0 mg/L | RR=3.5 |
| Haverkate et al 1997 | 2,121 | Sudden death/MI | 3.6 mg/L | RR=2.0 |
Abbreviations: CRP, C-reactive protein; HR, hazard ratio; MI, myocardial infarction; Mid-term, in-hospital, 3–37 months; OR, odds ratio; RR, relative risk; Short term, in-hospital, 3 months; UA, unstable angina; urg. revasc, urgent revascularization.