Figure 2.

Design of the ACUITY trial. Patients with moderate to high risk ACS were first randomized to one of three groups. For the groups including a GPI, asecond randomization occurred to either up-stream or deferred GPI. Angiography was undertaken within 72 hours, and patients were then treated medically,surgically or with (PCI) on clinical grounds.

Abbreviations: ACS, acute coronary syndrome; CABG, coronary artery bypass graft; GPI, glycoprotein IIb/IIIa inhibitor; PCI, percutaneous coronary intervention.