Blood pressure after 3–6 months of treatment with the fixed perindopril/in-dapamide (Per/Ind) combination. Per/Ind was initiated in newly diagnosed hypertensive patients (Initiation Group, n = 7032), replaced previous treatment in patients whose blood pressure (BP) was uncontrolled at inclusion and/or who experienced side-effects (Replacement Group, N = 7,423), or added to previous treatment in patients who were treated but only partially controlled (Add-on Group, n = 3483). Panel A: BP normalization was defined as a systolic BP ≤140 mm Hg and a diastolic BP ≤90 mm Hg. Panel B: Changes in SBP; Panel C: Changes in DBP. Data were missing in 1% of patients in each group.