Table 1.
Baseline characteristics of the patients
| Initiation n = 7032 | Replacement n = 7423 | Add-on n = 3483 | Total n = 17938 | |
|---|---|---|---|---|
| Agea in years, mean ± SD | 58.2 ± 11.2 | 63.1 ± 11.2 | 65.2 ± 10.7 | 61.6 ± 11.5 |
| Genderb, % male | 56.9 | 51.0 | 54.8 | 54.0 |
| Previous antihypertensive treatment, % | ||||
| Diuretic | − | 27.3 | 21.9 | 25.6 |
| Beta-blocker | − | 21.0 | 47.3 | 29.4 |
| Calcium inhibitor | − | 27.9 | 48.6 | 34.5 |
| ACE inhibitor | − | 25.2 | 14.4 | 21.8 |
| ATII inhibitor | − | 13.7 | 8.3 | 11.9 |
| Central acting | − | 7.1 | 14.7 | 9.5 |
| Other Vasodilators | − | 1.9 | 3.2 | 2.3 |
| SBPb in mm Hg | ||||
| Mean ± SD | 165.2 ± 11.9 | 159.4 ± 14.0 | 162.8 ± 12.2 | 162.3 ± 13.1 |
| Severityb | ||||
| ≤140 mm Hg, % | 1.0 | 10.1 | 1.2 | 4.8 |
| >150 mm Hg, % | 86.9 | 69.2 | 79.6 | 78.1 |
| DBPb in mm Hg | ||||
| mean±SD | 95.6 ± 8.7 | 91.9 ± 9.2 | 93.2 ± 9.0 | 93.6 ± 9.1 |
| DBPb≤ 90 mm Hg, % | 35.4 | 52.8 | 47.8 | 45.0 |
a
Data were missing in <3% of patients.
b
Data were missing in <1% of patients.
Abbreviations: ACE, angiotensin converting enzyme;ATII, angiotensin-receptor II; DBP, diastolic blood pressure; SBP, systolic blood pressure.