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Heart rate during treatment in the COMET trial. Copyright © 2003. Reproduced with permission from Poole-Wilson PA, Swedberg K, Cleland JG, etal. 2003. Comparison of carvedilol and metoprolol on clinical outcomes inpatients with chronic heart failure in the Carvedilol Or Metoprolol EuropeanTrial (COMET): randomised controlled trial. Lancet, 362:7–13.
Abbreviations: COMET, The Carvedilol Or Metoprolol European Trial. *p=0.0022, †p=0.034, ‡p=0.0040.
