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. 2007 Feb;3(1):93–98.

Table 1.

Baseline characteristics and side-effects of both ADEP and DAVID trials

ADEP study DAVID study
Picotamide Placebo Picotamide Aspirin

Dosage 300 mg bid 600 mg bid 320 mg od
Clinical characteristics
n = 1150 n = 1154 n = 603 n = 606
Age 63.4 + 7.3 62.9 + 7.4 63.8 + 7.2 64.6 + 7.3
Diabetes 20% 18% 100% 100%
PAD 100% 100% 100% 100%
Smoke 39.6% 37.1% 30.5% 28.4%
Hypertension 34.5% 37.5% 58.2% 55.6%
Dyslipidemia 36.5% 35.8% 38% 38.4%
Previous stroke 1.4% 1.7% 10.4% 10.2%
Coronary heart disease 15% 12.7% 19.4% 19%
Side-effects
Gastro-intestinal 11.1% 12% 10.9% 18.3%
Total 14.3% 13.5% 25.6% 33.9%

Abbreviations: bid, twice a day; od, once a day; PAD, peripheral artery disease.