Fig. 5.
Immunohistochemical detection of vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) in medulloblastoma specimens. Formalin-fixed, paraffin-embedded medulloblastoma specimens were reacted with specific polyclonal antibodies against VEGF, VEGFR-1, or VEGFR-2. Immunohistochemical analysis was performed as described in Materials and Methods and demonstrated a diffuse cytoplasmic positivity for all of the targets. Scale bars = 10 μm.