Table 2.
Reactivation of latently infected GM-Ps in the presence of cytokines
| Factor | Expression | Reactivation
|
|||||
|---|---|---|---|---|---|---|---|
| Sample 1
|
Sample 2
|
Sample 3
|
|||||
| 6 wk | 10 wk | 6 wk | 11 wk | 6 wk | 11 wk | ||
| INF-γ | IE1-2/lacZ | −/− | +++/+++ | −/− | −/++ | −/− | ++/+++ |
| TNF-α | IE1-2/lacZ | −/− | ++/+++ | −/− | −/++ | −/− | −/+ |
| GM-CSF | IE1-2/lacZ | ND | ND | ND | ND | −/− | +/+ |
| IL-4 | IE1-2/lacZ | ND | ND | −/− | +/+ | −/− | −/− |
| None | IE1-2/lacZ | −/− | −/− | −/− | −/− | −/− | −/− |
Cytokine was present during weeks 4–6 p.i. Samples were taken 6, 10, and 11 weeks p.i. +++, 15–30%; ++, 5-15%, +, 0.1–5%, −, 0.1%; ND, not done.