Table 3.
Prognostic Factors for Recurrence-Free Survival
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75% Recurrence-Free Survival
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Univariate Analysis (p Value)
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Multivariate Analysis (p Value)
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Variable | Group | No. Patients (%) | % Recurrences from Total Cases | 30 m | 60 m | 120 m | 30 m | 60 m | 120 m | 30 m | 60 m | 120 m |
Age (years) | <55 | 47 (32) | 11 | NR | NR | 66 m | 0.1 | 0.02 | 0.002 | 0.008 | 0.001 | |
⩾55 | 102 (68) | 4 | NR | NR | NR | |||||||
Sex | Male | 43 (29) | 14 | NR | NR | 31 m | 0.01 | 0.08 | 0.05 | 0.4 | 0.2 | 0.6 |
Female | 106 (71) | 3 | NR | NR | NR | |||||||
Tumor location | Convexity | 36 (24) | 8 | NR | NR | 97 m | 0.05 | 0.2 | 0.1 | 0.5 | 0.7 | 0.9 |
Parasagittal or tentorial | 44 (29) | 9 | NR | NR | NR | |||||||
Ventricular | 3 (2) | 43 | 23 m | 23 m | 23 m | |||||||
Cranial base | 51 (34) | 2 | NR | NR | 41 m | |||||||
Spinal | 15 (10) | 0 | NR | NR | NR | |||||||
Histologic subtype | Meningotheliomatous | 107 (78) | 9 | NR | NR | NR | 0.2 | 0.2 | 0.3 | |||
Psammomatous | 17 (12) | 0 | NR | NR | NR | |||||||
Transitional | 13 (9) | 0 | NR | NR | NR | |||||||
Fibroblastic | 2 (1) | 0 | ||||||||||
Tumor size | <30 mm | 36 (24) | 6 | NR | NR | NR | <0.0001 | 0.004 | 0.003 | 0.008 | 0.01 | 0.003 |
30–50 mm | 64 (43) | 10 | NR | NR | 98 m | |||||||
>50 mm | 49 (33) | 25 | NR | NR | 97 m | |||||||
Simpson’s grade | 1 | 6 (4) | 17 | NR | NR | NR | 0.4 | 0.7 | 0.3 | |||
2 | 52 (35) | 4 | NR | NR | NR | |||||||
3 | 91 (61) | 7 | NR | NR | 97 m | |||||||
DNA ploidy status | DNA diploid | 126 (84) | 5 | NR | NR | NR | 0.4 | 0.9 | 0.6 | |||
DNA aneuploid | 23 (16) | 9 | NR | NR | 84 m | |||||||
% S phase + G2M tumor cells | ⩽1 | 43 (29) | 2 | NR | NR | NR | 0.8 | 0.8 | 0.8 | |||
>1 | 106 (71) | 5 | NR | NR | 97 m |
Abbreviations: NR, not reached; m, months.