Skip to main content
. Author manuscript; available in PMC: 2008 Jun 1.
Published in final edited form as: Gen Comp Endocrinol. 2007 May 26;152(2-3):165–175. doi: 10.1016/j.ygcen.2007.04.018

Figure 4.

Figure 4

illustrates the possible mechanisms that underlie VIP’s actions in SCN neurons. In all cases, we expect that VIP would activate VPAC2R to stimulate the AC/PKA signaling pathway. This VIP-activated cascade has at least three actions within the SCN including modulation of intrinsic voltage gated channels, presynaptic regulation of GABA release, and alterations in transcription via CREB.