Table 2.
Proinflammatory cytokine expression in colon of αv-tie2 mice before (3 weeks) and after (18 weeks) onset of histologically evident colitis
Mice | IFN-γ |
IL4 |
||
---|---|---|---|---|
3 weeks (P = 0.017) | 18 weeks (P = 0.086) | 3 weeks (P = 0.018) | 18 weeks (P = 0.079) | |
Control | 26 ± 4.7 | 26 ± 9.9 | 2.1 ± 0.58 | 1.3 ± 1.0 |
α v-tie2 | 326 ± 122 | 518 ± 236 | 268 ± 109 | 228 ± 105 |
Gene expression is relative to GAPDH, × 103. P values are from Student's t test.