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Differential cell counts in bronchoalveolar lavage fluid from Plg+/+, Plg+/− and Plg−/− mice 3 hours after ovalbumin (OVA) challenge on Day 21. Values are expressed as mean ± SEM; n = 8–16 mice/group. OVA induced an increase in neutrophils (open bars), lymphocytes (dotted bars), and eosinophils (solid bars) in Plg+/+ but not in Plg+/− or Plg−/− mice (p < 0.001 by analysis of variance). There was no difference in the macrophage (striped bars) counts between the genotypes.
