TABLE 2.
TIME COURSE OF CYTOKINE EXPRESSION IN BRONCHOALVEOLAR LAVAGE FLUID
| Genotype/Days of and Hours after Treatment | TNF-α (pg/ml) | IL-5 (pg/ml) |
|---|---|---|
| Day 15/3 h | ||
| Plg+/+-PBS | 4.6 ± 0.7 | 0 |
| Plg+/+-OVA | 26.2 ± 6 | 12 ± 7.9 |
| Plg−/−-OVA | 11.4 ± 8 | 1.5 ± 0.8 |
| Day 18/3 h | ||
| Plg+/+-PBS | 14.2 ± 2.3 | 0 |
| Plg+/+-OVA | 35.6 ± 9.9 | 14 ± 6.3 |
| Plg−/−-OVA | 16.9 ± 10.1 | 2.2 ± 1.7 |
| Day 21/1 h | ||
| Plg+/+-PBS | 11.3 ± 11.3 | 0 |
| Plg+/+-OVA | 57.1 ± 20 | 0 |
| Plg−/−-OVA | 6.7 ± 2.7 | 0 |
| Day 21/3 h | ||
| Plg+/+-PBS | 0.7 ± 0.7 | 0 |
| Plg+/+-OVA | 85.1 ± 13.3 | 39.9 ± 23.3 |
| Plg−/−-OVA | 26.6 ± 10 | 1.6 ± 0.5 |
Definition of abbreviations: OVA = ovalbumin; PBS = phosphate-buffered saline; TNF-α = tumor necrosis factor α.
n = 3–6 mice/group.