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. 2007 May 3;176(3):291–299. doi: 10.1164/rccm.200605-662OC

Figure 1.

Figure 1.

(A) Effect of air or 95% oxygen (O2) ± ethyl nitrite (ENO; 0.2–20 ppm) × 8 days, or 10 ppm nitric oxide (NO) × 8 days on body weight (left-hand bars: n = 16/group; †p < 0.05 vs. 8-day air; *p < 0.01 vs. 8-day O2 control group; +p < 0.05 vs. 95% O2 + 10 ppm ENO). Effect of air × 14 days or 95% O2 ± 10 ppm ENO or NO × 8 days, followed by recovery in air for 6 days, on body weight (right-hand bars: †p < 0.05 vs. air control group; *p < 0.005 vs. 14 days O2 control; +p < 0.05 vs. 95% O2 + 10 ppm ENO; mean + SEM). (B) Effect of air or 95% O2 ± 10 ppm ENO or NO × 8 days on whole-blood methemoglobin; mean + SEM; n = 6/group. (C) Effect of air or 95% O2 ± 10 or 20 ppm ENO or 10 ppm NO on S-nitroso concentration in lavage. Bars represent means of average values from four or five pups per treatment group.