TABLE 2.
BASELINE DEMOGRAPHICS
| Non-CV (n = 1163) | CV (n = 55) | p Value | |
|---|---|---|---|
| Age, yr | 66.5 ± 6.1 | 64.9 ± 7.0 | 0.061 |
| Sex, % female | 38.7 | 40 | 0.89 |
| FEV1, % | 26.7 ± 7.2 | 26.9 ± 6.8 | 0.87 |
| TLC, % | 128.5 ± 15.2 | 122.2 ± 11.9 | 0.0003 |
| RV, % | 222.3 ± 49.6 | 212.8 ± 44.9 | 0.16 |
| DlCO, % | 28.3 ± 9.7 | 29.0 ± 9.8 | 0.59 |
| PaO2, mm Hg | 64.3 ± 10.3 | 64.9 ± 10.8 | 0.67 |
| PaCO2, mm Hg | 43.1 ± 5.8 | 44.3 ± 5.6 | 0.14 |
| LowEX, % | 45.4 | 36.4 | 0.21 |
| UL predominant, % | 65.3 | 57.4 | 0.25 |
| 6MWD, ft | 1,216 ± 314 | 1,245 ± 324 | 0.51 |
| Max watts | 38.7 ± 21.4 | 46.1 ± 25.3 | 0.01 |
| BMI | 24.8 ± 3.9 | 24.5 ± 4.0 | 0.64 |
Definition of abbreviations: CV = cardiovascular (substudy); DlCO = diffusing capacity of carbon monoxide; LowEX = low exercise performance on cardiopulmonary exercise test (⩽ 40 W if male, ⩽ 25 W if female); Max watts = maximum wattage attained on cardiopulmonary exercise testing; Non-CV = NETT patients not enrolled in CV substudy or not completing the 6-month CV substudy evaluation; RV = residual volume; 6MWD = six-minute-walk distance; UL predominant; upper lobe predominant disease on computed tomography scan.