Table 4 Stratification analysis of rs7514863 in the complete dataset.
| Stratification | Proportion of the risk T allele [n] | Allelic association | ||
|---|---|---|---|---|
| Cases | Controls | OR (95% CI) | p Value | |
| Female | 0.19 [853] | 0.16 [1211] | 1.23 (1.04 to 1.44) | 0.013 |
| Male | 0.18 [408] | 0.16 [1149] | 1.17 (0.94 to 1.44) | 0.16 |
| RF positive* | 0.19 [912] | 0.16 [2463] | 1.20 (1.05 to 1.40) | 0.0072 |
| RF negative* | 0.19 [250] | 0.16 [2463] | 1.22 (0.96 to 1.55) | 0.1 |
| Erosive disease* | 0.18 [438] | 0.16 [2463] | 1.20 (0.99 to 1.44) | 0.06 |
| One copy of SE | 0.20 [470] | 0.15 [578] | 1.39 (1.11 to 1.75) | 0.0043 |
| Two copies of SE | 0.20 [285] | 0.14 [147] | 1.53 (1.05 to 2.25) | 0.029 |
| At least one copy of SE | 0.20 [755] | 0.15 [725] | 1.43 (1.18 to 1.73) | 0.0003 |
| Negative for SE | 0.17 [190] | 0.16 [827] | 1.03 (0.77 to 1.39) | 0.84 |
RF, rheumatoid factor; SE, shared epitope; OR, odds ratio; CI, confidence intervals.
Values in square brackets show number of individuals conforming to the corresponding characteristic.
*All controls were used in the analysis.