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. 2007 Feb 8;66(10):1276–1283. doi: 10.1136/ard.2006.058644

Table 5 Manual evaluation of major histocompatibility complex class I antigen expression on the surface of muscle fibres, and membranolytic attack complex deposits in capillaries and in necrotic muscle fibres, and on the surface of non‐necrotic fibres.

Patients/diagnosis MHC class I antigen MAC
Fibres Capillaries Fibres
B.T. After 24–48 h After third inf B.T. After 24–48 h After third inf B.T. After 24–48 h After third inf
1/PM + + + + ++ +
2/PM ++++ + ++ + + + ++ ++ +
3/PM + + + ++ ++ + +++ +++ +
4/PM +++++ +++++ NA ++ +++ NA + + NA
5/PM ++++ ++++ NA ++ + NA +++ + NA
6/PM + + ++ ++ +++ +
7/DM + + + + + + +++ ++ +
8/DM +++++ ++++ NA +++ ++ NA + NA
9/DM +++ +++++ NA ++ ++ NA ++ + NA
10/DM + NA + + NA ++ NA ++
11/JDM + NA + + NA + NA
12/IBM +++++ NA +++++ + NA + ++ NA ++
13/IBM + +++ +++++ ++ +++ +++ +

B.T., before treatment; DM, dermatomyositis; IBM, inclusion body myositis; Inf, infusion; JDM, juvenile onset dermatomyositis; NA, not available/assessable; PM, polymyositis.

Grading explanations are described in table 3. Individual changes after the third infusion: in major histocompatibility complex‐I, ⇔ 1–3, 6–7, 10–12 ⇑ 13; in membranolytic attack complex fibres, ⇔ 1–2, 6, 11–13 ⇓ 3, 7 ⇑ 10; in membranolytic attack complex capillaries, ⇔ all patients.