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letter
. 2007 Jul;56(7):1027–1028. doi: 10.1136/gut.2007.122333

Table 1 Characteristics of different determinants for selection for referral.

Determinant for selection for referral (% and 95% CI)
HBeAg+ or ALT+ HBeAg+ ALT+ in HBeAg−
Prevalence of determinant 43 (38 to 48) 15 (12 to 19) 33 (28 to 38)
Positive predictive value* 45 (38 to 53) 88 (78 to 94) 22 (15 to 30)
Negative predictive value† 95 (91 to 97) 90 (86 to 92) 95 (91 to 97)
Sensitivity‡ 87 (80 to 93) 61 (51 to 70) 68 (51 to 80)
Specificity§ 70 (64 to 74) 98 (95 to 99) 71 (66 to 76)

ALT, alanine aminotransferase; HBeAg, hepatitis B e‐antigen; −, negative; +, positive.

*Proportion of patients selected for referral who had high viral loads.

†Proportion of patients not selected for referral who had low viral loads.

‡Proportion of patients with high viral loads who were selected for referral.

§Proportion of patients with low viral loads who were not selected for referral.