Table 3 Time dependent analysis of all‐cause mortality, including both diabetes at baseline and new onset diabetes as a time dependent factor. CAD removed, paced rhythm added and CAD removed, AF added.

	RR (95% CI)	p Value
Carvedilol v metoprolol	0.792 (0.698 to 0.899)	0.0003
Diabetes	1.2 (1.046 to 1.377)	0.0095
↑ Age (per year)	1.031 (1.023 to 1.038)	<0.0001
Female v male	0.722 (0.603 to 0.863)	0.0004
↑ Weight (per kg)	0.992 (0.987 to 0.997)	0.0033
Systolic BP >120 mm Hg	0.763 (0.667 to 0.873)	0.0001
NYHA III v II	1.429 (1.246 to 1.639)	<0.0001
NYHA IV v II	1.722 (1.294 to 2.293)	0.0002
↑ Duration of HF (per month)	1.001 (1 to 1.002)	0.0044
↑ LVEF (per%)	0.976 (0.967 to 0.985)	<0.0001
Previous MI	1.344 (1.167 to 1.548)	<0.0001
Stroke	1.238 (0.997 to 1.538)	0.0536
AF	0.988 (0.835 to 1.169)	0.8901
Digitalis	1.45 (1.263 to 1.666)	<0.0001
Antiarrhythmic drugs	1.556 (1.308 to 1.851)	<0.0001
Nitrates	1.15 (1.003 to 1.318)	0.0447
Lipid lowering	0.767 (0.647 to 0.908)	0.0021
↑ Haemoglobin (g/l)	0.924 (0.885 to 0.965)	0.0003
↑ Sodium (mmol/l)	0.949 (0.933 to 0.965)	<0.0001
↑ Creatinine (μmol/l)	1.002 (1.001 to 1.003)	<0.0001

CAD, coronary artery disease; AF, atrial fibrillation.