Table 1 Comparison of morphometric measurements of cuffed artery segments at cuff replacement (basal) and from 14‐day control DEC, SEC and PEC (14 days normal cuff plus 14 days DEC).
| Intimal thickening (×103 μm2) | Intima/media ratio | Lumen stenosis (%) | Medial area (×103 μm2) | |
|---|---|---|---|---|
| Basal | 6.8 (1.2)* | 0.49 (0.10)* | 24.0 (5.0)* | 15.9 (1.3) |
| Control DEC | 15.5 (1.1) | 1.43 (0.15) | 65.3 (4.4) | 12.1 (1.1) |
| 1% SEC | 7.4 (0.9)* | 0.54 (0.07)* | 34.7 (3.3)* | 13.1 (1.3) |
| 2.5% SEC | 9.3 (1.4)* | 0.75 (0.11)* | 38.9 (3.9)* | 12.4 (0.7) |
| 1% PEC | 9.9 (1.5)* | 0.68 (0.07)* | 36.9 (7.8)* | 15.2 (0.6) |
| 2.5% PEC | 9.3 (2.1)* | 0.65 (0.14)* | 33.6 (8.9)* | 12.3 (1.0) |
Values are mean (SEM); n = 8/group.
DEC, drug‐eluting cuff; SEC, sirolimus‐eluting cuff; PEC, paclitaxel‐eluting cuff.
*p<0.05 vs control DEC.