Table 2 Comparison of haemodynamic data at baseline, intervention and recovery in the total cohort (n = 22).
| Variable | Baseline | Intervention | Recovery |
|---|---|---|---|
| Haemodynamic variables | |||
| Heart rate (bpm) | 62 (8) | 67 (12)* | 62 (13) |
| Systolic BP (mm Hg) | 143 (14) | 181 (20)† | 136 (15)* |
| Diastolic BP (mm Hg) | 77 (9) | 92 (8)† | 75 (8) |
| Mean BP (mm Hg) | 99 (8) | 121 (10)† | 96 (7)* |
| Stroke volume (ml) | 104 (19) | 100 (22) | 103 (19) |
| Qmean (ml/s) | 323 (67) | 306 (66)* | 324 (65) |
| Cardiac output (l/min) | 6.34 (1.31) | 6.55 (1.51) | 6.16 (1.22) |
| SAC (ml/mm Hg) | 1.66 (0.47) | 1.16 (0.31)† | 1.82 (0.60)* |
| SVR (dyne×s/cm5) | 1294 (264) | 1552 (372)† | 1280 (233) |
| Stenotic indices | |||
| ΔPmean (mm Hg) | 36 (13) | 36 (14) | 35 (14) |
| AVA (cm2) | 1.15 (0.32) | 1.09 (0.33)* | 1.17 (0.33) |
| Resistance (dyne×s/cm5) | 153 (63) | 164 (74)* | 146 (62) |
| % LVSW loss (%) | 19.8 (6.3) | 16.5 (5.7)† | 20.0 (7.1) |
| ELCo (cm2) | 1.32 (0.40) | 1.24 (0.42)* | 1.34 (0.43) |
| Change from baseline | |||
| Qmean (ml/s) | –17 (31) | 1 (31) | |
| ΔPmean (mm Hg) | 0 (3) | –1 (3) | |
| AVA (cm2) | –0.06 (0.11) | 0.02 (0.11) | |
| Resistance (dyne×s/cm5) | 11 (21) | –7 (26) | |
| % LVSW loss (%) | –3.3 (1.7) | 0.2 (2.3) | |
| ELCo (cm2) | –0.08 (0.17) | 0.02 (0.16) |
AVA, aortic valve area; BP, blood pressure; ELCo, energy loss coefficient; % LVSW loss, percentage left ventricular stroke work loss index; ΔPmean, mean transvalvular pressure gradient; Qmean, mean transvalvular flow rate; SAC, systemic arterial compliance; SVR, systemic vascular resistance.
Values in parentheses are the SD.
*p<0.05 vs baseline.
†p<0.001 vs baseline.