Table 3 The spectrum of lesions with a cribriform appearance.
| Lesion | Basal cells | Cytonuclear features | Distension of duct | Outline of duct |
|---|---|---|---|---|
| Hyperplasia | Present | Bland | None or slight | Smooth |
| H‐PIN | Present | Nucleoli | None or slight | Smooth |
| Intraductal carcinoma | Present | Nucleoli | Distended | Smooth |
| Grade 3 adenocarcinoma | Absent | Nucleoli | Slight | Smooth |
| Grade 4 adenocarcinoma | Absent | Nucleoli | Distended | Irregular, or outpouchings |
| Ductal adenocarcinoma | Absent, rare | Nucleoli, tall columnar cells | Distended | Often smooth |
H‐PIN, high‐grade prostatic intraepithelial neoplasm.