Table 2 Leptin expression in colorectal cancer and clinicopathological characteristics of patients.
| Clinicopathological features | Leptin expression | p‐Value | ||
|---|---|---|---|---|
| 0 | 1+ | 2+ | ||
| n = 81 | n = 56 | n = 29 | ||
| Age (years) | ||||
| ⩽60 (n* = 52) | 25 (48.1%) | 16 (30.8%) | 11 (21.1%) | 0.672 |
| >60 (n* = 114) | 56 (49.1%) | 40 (35.1%) | 18 (15.8%) | |
| Gender | ||||
| Male (n* = 88) | 41 (46.6%) | 33 (37.5%) | 14 (15.9%) | 0.539 |
| Female (n* = 78) | 40 (51.3%) | 23 (29.5%) | 15 (19.2%) | |
| Tumour localisation | ||||
| Rectum (n* = 79) | 38 (48.2%) | 26 (32.9%) | 15 (18.9%) | 0.885 |
| Colon (n = 87; 100%) | 43 (49.4%) | 30 (34.5%) | 14 (16.1%) | |
| Histological type | ||||
| Adc (n* = 141) | 66 (46.8%) | 46 (32.6%) | 29 (20.6%) | 0.044 |
| Adc muc (n* = 25) | 15 (60.0%) | 10 (40.0%) | 0 (0%) | |
| Histological differentiation | ||||
| G2 (n* = 118) | 51 (43.2%) | 39 (33.1%) | 28 (23.7%) | 0.002 |
| G3 (n* = 48) | 30 (62.5%) | 17 (35.4%) | 1 (2.1%) | |
| Tumour size | ||||
| pT1+pT2 (n* = 17) | 7 (41.2%) | 7 (41.2%) | 3 (17.6%) | 0.764 |
| pT3+pT4 (n* = 149) | 74 (49.7%) | 49 (32.9%) | 26 (17.4%) | |
| Lymph node involvement | ||||
| Negative (n* = 82) | 40 (48.8%) | 26 (31.7%) | 16 (19.5%) | 0.746 |
| Positive (n* = 84) | 41 (48.8%) | 30 (35.7%) | 13 (15.5%) | |
n*, number of cases taken as 100%.
Adc, adenocarcinoma; Adc muc, adenocarcinoma mucinosum.