Table 4 HPV16 integration in E2 and viral load as compared to diagnosis and percentage of laminin‐5 immunoreactive cells.
| Sample no | Diagnosis | Viral load (E6)* | % Integrated | Copies integrated† | % Laminin‐5 | Laminin‐5 stromal |
|---|---|---|---|---|---|---|
| 3 | Normal | 0.13 | 96 | 0.12 | 0 | a |
| 4 | Normal | 0.01 | 84 | 0.01 | 0 | a |
| 5 | SCC | 10.60 | 35 | 3.74 | 100 | p |
| 6 | CIN3 | 0.02 | 100 | 0.02 | 0 | a |
| 8 | SCC | 3.77 | 66 | 2.49 | 100 | p |
| 9 | SCC | 16.60 | 90 | 14.86 | 100 | p |
| 11 | CIN3 | 0.18 | 92 | 0.16 | 0 | a |
| 12 | CIN3 | 0.79 | 68 | 0.54 | 10 | p |
| 13 | CIN3 | 0.30 | 92 | 0.28 | 0 | a |
| 14 | CIN3 | 0.03 | 98 | 0.03 | 0 | a |
| 16 | SCC | 0.81 | 95 | 0.76 | 60 | p |
| 19 | CIN3 | 3.44 | 80 | 2.75 | 0 | a |
| 20 | CIN3 | 0.85 | 90 | 0.76 | 0 | a |
| 22 | CIN3 | 5.97 | 57 | 3.39 | 0 | a |
| 23 | SCC | 36.40 | 90 | 32.87 | 42 | p |
| 25 | SCC | 1.82 | 61 | 1.10 | 100 | p |
| 26 | Normal | 0.10 | 96 | 0.10 | 0 | a |
| 29 | Normal | 0.08 | 67 | 0.05 | 0 | a |
| 30 | CIN3 | 1.37 | 68 | 0.94 | 80 | a |
HPV, human papillomavirus; CIN, cervical intraepithelial neoplasia; SCC, squamous cell carcinoma.
Laminin‐5 immunoreactive cells in stromal tissue: a, absent; p, present.
*Normalised ratio.
†Number of copies integrated in E2 for one glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) gene.