Table 2 Relationship between clinicopathological features and neutrophil gelatinase‐associated lipocalin expression level in oesophageal squamous cell carcinoma by western blot.
| Parameters | NGAL expression level (ng/100 μg, mean (SD)) | p Value |
|---|---|---|
| Mean age, years (range) | ||
| <57 | 0.990 (1.036) (n = 37) | 0.364 |
| >57 | 0.775 (0.973) (n = 36) | |
| Gender | ||
| Male | 0.931 (1.039) (n = 62) | 0.345 |
| Female | 0.618 (0.765) (n = 11) | |
| Primary tumour | ||
| T1/T2 | 0.571 (0.669) (n = 19) | 0.126 |
| T3/T4 | 0.981 (1.081) (n = 54) | |
| Regional lymph node | ||
| N0 | 0.938 (1.806) (n = 36) | 0.593 |
| N1 | 0.812 (0.930) (n = 37) | |
| Distant metastasis | ||
| M0 | 0.906 (1.013) (n = 69) | 0.436 |
| M1 | 0.500 (0.867) (n = 4) | |
| Stage | ||
| I/IIA/IIB | 0.793 (0.955) (n = 33) | 0.486 |
| III/IV | 0.959 (1.049) (n = 40) | |
| Histopathology | ||
| Normal tissue | 0.549 (0.918) (n = 73) | 0.030 |
| ESCC tissue | 0.874 (1.002) (n = 73) | |
| Well differentiated (G1) | 1.504 (1.209) (n = 14) | p1/2 = 0.017 |
| Moderately differentiated (G2) | 0.751 (0.934) (n = 46) | p2/3 = 0.677 |
| Poorly differentiated (G3) | 0.632 (0.766) (n = 13) | p1/3 = 0.036 |
ESCC, oesophageal squamous cell carcinoma; NGAL, neutrophil gelatinase‐associated lipocalin.