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. 2007 May 8;194(1):161–170. doi: 10.1677/JOE-07-0090

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© 2007 Society for Endocrinology

This is an Open Access article distributed under the terms of the Society for Endocrinology's Re-use Licence which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Corticosterone treatment increases blood pressure in Pomc^−/− mice: effect of CORT treatment on the Renin-angiotensin system. Effect of 10 days corticosterone treatment (cort) on (A) systolic blood pressure, (B) renin concentration, (C) plasma angiotensinogen, (D) angiotensinogen (Agt) mRNA in adipose tissue (AT), and (E) angiotensinogen (Agt) mRNA levels in liver in wild-type (+/+) and Pomc^−/− (−/−) mice. Epi, epididymal fat; ing, inguinal fat; retro, retroperitoneal fat. Data are means±s.e.m., and for transcript levels are expressed relative to levels in untreated wild-type mice (100%); n=5 per group. Significance *P<0·05, **P<0·01 and ***P<0·001.