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. 2007 Sep 28;3(9):e161. doi: 10.1371/journal.pgen.0030161

Figure 4. Surrogate Variables from Human Studies.

Figure 4

(A) A plot of the top surrogate variable estimated from the breast cancer data [22]. The BRCA1 group is relatively homogeneous (triangles), but the BRCA2 group shows substantial heterogeneity (pluses).

(B) A plot of tissue type versus array for the Rodwell et al. [7] study (dotted line) and the top surrogate variable estimated from the expression data when tissue was ignored (dashed line). There is strong correlation between the top surrogate variable and the tissue type variable.