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. Author manuscript; available in PMC: 2008 May 18.
Published in final edited form as: J Mol Biol. 2007 Mar 6;368(5):1392–1402. doi: 10.1016/j.jmb.2007.02.081

Figure 5.

Figure 5

Antibody combining site of RS2-1G9 (stereoview). Hydrogen bonds are shown as broken lines. Only Fab side chains that contact the lactam ligand (pink) are displayed. The hapten analog satisfies all its functional groups, except for the amide group of the lactam, which is crucial for the observed cross-reactivity of this antibody with an N-acyl homoserine lactone. A plethora of aromatic side chains surrounds the ligand. The residues between LeuH97 and AsnH100 of CDR H3 are omitted for clarity.