Table 3 Association between glutathione S transferase genotype profile and the development of primary open angle‐glaucoma.
GSTM1 | GSTT1 | Patients with glaucoma n (%) | Controls n (%) | OR (95% CI) |
---|---|---|---|---|
Present | Present | 59 (40.9%) | 53 (43.8%) | 1 (Reference)* |
Present | Null | 54 (37.5%) | 14 (11.5%) | 3.46 (1.64 to 7.38) |
Null | Present | 15 (10.5%) | 46 (38.0%) | 0.29 (0.13 to 0.61) |
Null | Null | 16 (11.1%) | 8 (6.7%) | 0.55 (0.20 to 1.52) |
GST, glutathione S transferase.
*Reference group; individuals with two putative low‐risk genotypes (the presence of GSTM1 (non‐deleted) and GSTT1 (non‐deleted)).