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. Author manuscript; available in PMC: 2008 Jul 2.
Published in final edited form as: Brain Res. 2007 Apr 22;1156:31–45. doi: 10.1016/j.brainres.2007.04.043

Table 2. Results of statistical analyses of dopamine receptor expression levels at each of E12 to P60 in each brain region.

Statistical analyses of differences among dopamine receptor expression levels at each age. For each brain region and age, expression levels of the five receptors (D1R, D2R, D3R, D4R and D5R) were analyzed by ANOVA. Differences between a given receptor pair were analyzed by Bonferroni post-test. NS = not significant, for ANOVA p>0.001 for Bonferroni p>0.05.

Striatum Globus Pallidus
E12 E15 P0 P21 P60 P0 P21 P60
ANOVA (all 5 receptors) F(dfbtw, dfw) NS(p=0.0022) 11.41 (4,8) p<0.0001 27.95 (4,15) p<0.0001 183.4 (4,55) p<0.0001 394.8 (4,69) p<0.0001 767.5 (4,115) ANOVA (all 5 receptors) F(dfbtw, dfw) p<0.0001 64.75 (4,10) p<0.0001 87.95 (4,15) p=0.0001 9.035 (4,25)
D1R vs D2R NS p< 0.001 p< 0.001 p< 0.001 D1R vs D2R p< 0.001 p< 0.001 p< 0.01
D1R vs D3R p< 0.001 p< 0.001 p< 0.001 p< 0.001 D1R vs D3R NS NS NS
D1R vs D4R p< 0.001 p< 0.001 p< 0.001 p< 0.001 D1R vs D4R NS p< 0.05 NS
D1R vs D5R p< 0.001 p< 0.001 p< 0.001 p< 0.001 D1R vs D5R NS p< 0.05 NS
D2R vs D3R p< 0.001 p< 0.001 p< 0.001 p< 0.001 D2R vs D3R p< 0.001 p< 0.001 p< 0.001
D2R vs D4R p< 0.001 p< 0.001 p< 0.001 p< 0.001 D2R vs D4R p< 0.001 p< 0.001 p< 0.001
D2R vs D5R p< 0.001 p< 0.001 p< 0.001 p< 0.001 D2R vs D5R p< 0.001 p< 0.001 p< 0.001
D3R vs D4R NS NS NS NS D3R vs D4R NS NS NS
D3R vs D5R NS NS NS NS D3R vs D5R NS NS NS
D4R vs D5R NS NS NS NS D4R vs D5R NS NS NS
Frontal cortex Cingulate cortex
E15 P0 P21 P60 P0 P21 P60
ANOVA (all 5 receptors) F(dfbtw, dfw) p<0.0001 68.8 (4,25) p<0.0001 44.02 (4,9) p<0.0001 31.63 (4,15) p<0.0001 33.89 (4,24) ANOVA (all 5 receptors) F(dfbtw, dfw) p<0.0001 72.25 (4,10) p<0.0001 45.11 (4,14) p<0.0001 13.02 (4,21)
D1R vs D2R p< 0.001 p< 0.001 p< 0.01 p< 0.001 D1R vs D2R NS p< 0.01 p< 0.01
D1R vs D3R p< 0.001 p< 0.001 p< 0.001 p< 0.001 D1R vs D3R p< 0.001 p< 0.001 p< 0.001
D1R vs D4R p< 0.001 p< 0.001 p< 0.001 p< 0.001 D1R vs D4R p< 0.001 p< 0.001 p< 0.001
D1R vs D5R p< 0.001 p< 0.001 p< 0.001 p< 0.001 D1R vs D5R p< 0.001 p< 0.001 p< 0.001
D2R vs D3R NS NS p< 0.01 p< 0.01 D2R vs D3R p< 0.01 p< 0.01 NS
D2R vs D4R NS NS p< 0.01 p< 0.05 D2R vs D4R p< 0.001 p< 0.01 NS
D2R vs D5R NS NS p< 0.05 p< 0.05 D2R vs D5R p< 0.01 p< 0.01 NS
D3R vs D4R NS NS NS NS D3R vs D4R p< 0.001 NS NS
D3R vs D5R NS NS NS NS D3R vs D5R NS NS NS
D4R vs D5R NS NS NS NS D4R vs D5R p< 0.001 NS NS