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The cumulative release of BCNU into a well-stirred reservoir as a function of time (a) and the square root of time (b). The linear portion indicated in b is indicative of diffusion controlled release from a planar geometry. Reprinted with permission from Springer Science and Business Media: Fung, L. K. et al. Chemotherapeutic drugs released from polymers: distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea in the rat brain. Figure 2. Pharmaceutical Research. 1996;13:671-82.
