Table 1.

Approximate Blood Glucose Concentrations for Counterregulatory Hormonal and Physiologic, Somatic, and Cognitive (Neuroglycopenic) Responses in Persons Without Diabetes

Response	Glucose mg/dL (mmol/L)
Inhibition of endogenous insulin secretion	83 (4.6)
Counterregulatory hormone release (glucagon, epinephrine)	68 (3.8)
Onset of autonomic and neuroglycopenic symptoms	58–50 (3.2–2.8)
Neurophysiologic dysfunction, evoked responses	54–43 (3.0–2.4)
Widespread electroencephalographic changes	54 (3.0)
Cognitive dysfunction, inability to perform complex tasks	50 (2.8)
Severe neuroglycopenia, reduced conscious level, seizures, coma	27 (< 1.5)

Data from Zammitt and Frier[15]