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. 1998 Mar 31;95(7):3984–3989. doi: 10.1073/pnas.95.7.3984

Figure 4.

Figure 4

Cdc42-induced apoptosis requires AP-1 activity. pCDFLAGΔ169 (0.4 mg/ml), 0.1 mg/ml V12Cdc42, and 70 kDa Texas Red Dextran were coinjected into SCG neurons. The cells were maintained in the presence of NGF, and the percentage of surviving cells was assessed 48 hr later. The results are the means of three independent experiments ± SEM. FLAGΔ169 blocked V12Cdc42-induced death.