Table 2.
Multivariate Linear Regression Analysis Relating Periodontitis With Log Plasma CRP Levels (mg/l) Measured in Early Pregnancy*
| Adjusted Mean CRP† (SE)
|
|||||
|---|---|---|---|---|---|
| Model | Periodontitis (≥1 site with alveolar bone loss ≥3 mm) | No Periodontitis (<1 site with alveolar bone loss ≥3 mm) | Difference (%) (95% CI) | P Value | R2 |
| All participants (33 cases; 63 controls) | 2.46 (0.52) | 1.49 (0.22) | 65.4 (−2.2, 179.8) | 0.06 | 0.27 |
| Restricted to participants whose radiographs were taken before blood collection (28 cases; 54 controls) | 2.43 (0.58) | 1.43 (0.24) | 69.7 (−5.7, 205.4) | 0.08 | 0.31 |
Adjusted for gestational age at blood collection (weeks), age (years), race/ethnicity (white versus other), completion of college education (yes/no), annual household income more than $70,000 (yes/no), pre-pregnancy BMI (kg/m2), and alcohol intake at first trimester of pregnancy (g/day).
Adjusted means in multivariate model were computed using least square means procedures, holding all covariates to their average values, and back-transformed to original scale.