TABLE 3.
Birth outcomes according to quartile of combined DHA* + EPA* intake in each trimester: unadjusted data from pregnant women from Massachusetts enrolled in Project Viva, 1999–2002
| Quartile of combined DHA + EPA intake | Continuous outcomes
|
|||
|---|---|---|---|---|
| DHA + EPA intake in g/day (mean (range)) | Birth weight in g (mean (SD*)) | Fetal growth z value (mean (SD)) | Days of gestation (median (25th percentile, 75th percentile)) | |
| First trimester (n = 1,797) | ||||
| Quartile 1 | 0.02 (0–0.05) | 3,520 (609) | 0.28 (1.0) | 276 (272, 285) |
| Quartile 2 | 0.09 (0.06–0.12) | 3,472 (564) | 0.19 (1.0) | 276 (271, 284) |
| Quartile 3 | 0.18 (0.12–0.24) | 3,462 (582) | 0.15 (1.0) | 277 (272, 285) |
| Quartile 4 | 0.36 (0.24–2.53) | 3,421 (560) | 0.10 (0.9) | 278 (272, 283) |
| p† for trend | 0.01 | 0.003 | 1.0 | |
| Second trimester (n = 1,663) | ||||
| Quartile 1 | 0.02 (0–0.05) | 3,523 (562) | 0.25 (1.0) | 277 (272, 285) |
| Quartile 2 | 0.09 (0.06–0.12) | 3,541 (526) | 0.28 (1.0) | 277 (272, 285) |
| Quartile 3 | 0.18 (0.12–0.23) | 3,447 (537) | 0.10 (0.9) | 277 (272, 285) |
| Quartile 4 | 0.38 (0.24–2.71) | 3,461 (546) | 0.13 (1.0) | 277 (272, 284) |
| p† for trend | 0.02 | 0.009 | 0.27 | |
| Third trimester (n = 2,070) | ||||
| Quartiles 1 + 2 | 0.05 (0–0.06) | 3,507 (563) | 0.23 (1.0) | 279 (272, 284) |
| Quartile 3 | 0.09 (0.06–0.11) | 3,473 (598) | 0.20 (1.0) | 276 (272, 284) |
| Quartile 4 | 0.27 (0.11–1.72) | 3,394 (597) | 0.06 (1.0) | 275 (272, 283) |
| p† for trend | 0.0003 | 0.002 | 0.01 | |
*
DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; SD, standard deviation.
†
Two-sided p value.