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. Author manuscript; available in PMC: 2007 Sep 27.
Published in final edited form as: Dev Biol. 2006 Dec 2;303(2):601–610. doi: 10.1016/j.ydbio.2006.11.035

Fig. 3. Loss of rostral RA activity does not affect expression of Meis2, a marker of forebrain intermediate character.

Fig. 3

(A-B) Rescue of Raldh2-/- early lethality by maternal RA treatment from E6.75-E8.5 does not stimulate RA activity in the forebrain or other head tissues. (C-F) Coronal sections through the telencephalon showing that Meis2 expression is not significantly affected in E10.5 single mutants or Raldh2-Raldh3 double null mutants (R2-/-:R3-/-) rescued by maternal RA treatment from E6.75-E8.5 (which does not stimulate RA activity in the forebrain as shown in panel A). f, forebrain telencephalic vesicles.