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. Author manuscript; available in PMC: 2008 Aug 1.
Published in final edited form as: Cell Calcium. 2007 Mar 27;42(2):183–191. doi: 10.1016/j.ceca.2007.01.012

Fig. 2.

Fig. 2

ARC channel activity is selectively inhibited by an antibody targeted to the exposed extracellular N-terminal of plasma membrane STIM1. (A) Currents via CRAC channels and ARC channels recorded following incubation with a control IgG2 antibody (IgG – green) compared to those recorded following an identical incubation with an N-terminal STIM1 antibody (Ab – brown). (B) Representative current-voltage relationships of the currents through the ARC channels following incubation with the relevant antibodies. All incubations were for 30-40 minutes at room temperature and at an antibody concentration of 5 μg ml−1. Other details as in Fig. 1. Data redrawn from [21].