Skip to main content
. Author manuscript; available in PMC: 2008 Aug 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2007 Jan 12;222(3):271–280. doi: 10.1016/j.taap.2006.12.034

Fig. 1.

Fig. 1

Hepatocellular carcinoma (HCC) incidence (left) and multiplicity (right) in adult male C3H mice exposed to arsenic in utero. The indicated maternal arsenic dose in the drinking water was given between gestation day 8 and 18 (see Methods for details). Incidence is the number of HCC bearing mice/number of mice available for examination. Multiplicity is defined as the average number of HCC per mouse and expressed as the mean ± SEM. An asterisk indicates a significant difference from control (p ≤ 0.05). Dose-related trend p values are shown. See Methods for specific statistical tests. Modified from Waalkes et al. (2003).