Figure 5.
(A). Polarized transport of [3H]-cyclosporine-A in SV40-HCEC from A→B as compared from B→A direction. (B). A→B and B→A permeability of [3H]-cyclosporine-A in SV40-HCEC in the presence of MK-571 (75 μM). Each data point represents the mean ± SD of three determinations. Statistical significance was tested by two-factor ANOVA. *P ≤ 0.05; **P ≤ 0.01.