Table 2.
Low ThD Patients
n=11 |
High ThD Patients
n=10 |
|||
---|---|---|---|---|
M | SD | M | SD | |
Age (years) | 33.64 | 6.78 | 31.60 | 8.33 |
WAIS-R IQ | 97.91 | 15.63 | 91.20 | 8.99 |
WRAT-R IQ | 105.64 | 11.74 | 106.30 | 10.24 |
BPRS^ | 32 (range 20-46) | 7.67 | 40 (range 19-62) | 15.02 |
Neuroleptic medication | 9 | 5 | ||
-clozapine/olanzapine | 4 | 5 | ||
- risperidone | 5 | 0 | ||
- high potency drug*** | 0 | 1 | ||
- anticholinergics | 4 | 0 | ||
- adjunctives**** | 5 | 4 | ||
TLC scores | N/A | |||
- global # | 1.30 (range 0-1.75) | 0.53 | 2.75 (range 2-3.75) | 0.59 |
- poverty of speech | 0.64 (range 0-2) | 0.81 | 1.00 (range 0-3) | 1.07 |
Patient groups were matched on age (p>.5), WRAT-R (p>.5) and WAIS-R (p>.1). There were twenty-four healthy control participants (11 females, 13 males) mean age 31.17 years (SD=9.34). Their mean score on the WRAT-R was 109.36 (SD=11.47) and on the WAIS-R was 111.65 (SD=13.21).
= haloperidol
=lithium, depakote, sertraline, lorazepam, venlafaxine, clonazepam, buspirone
The Brief Psychiatric Rating Scale (Overall & Gorham, 1962) – total score exclusive of conceptual disorganization.