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Structures of antisense building blocks. Structures of the building blocks for unmodified oligodeoxynucleotides (ODNs), methylphosphonate oligonucleotides (MPOs), locked nucleic acids (LNAs), 2'-O-methylribonucleotides (2'-OMes), phosphorothioate-linked 2'-deoxy-2'-fluoro-D-arabinonucleic acids (PS-FANAs), phosphorothioate oligonucleotides (PS-ODNs), peptide nucleic acids (PNAs), and phosphorodiamidate morpholino oligomers (PMOs). All examples include an adenine base.
