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. Author manuscript; available in PMC: 2007 Oct 1.
Published in final edited form as: Pharmacol Biochem Behav. 2007 Apr 3;87(1):1–10. doi: 10.1016/j.pbb.2007.03.014

Figure 7.

Figure 7

Analyses designed to clarify the basis for reduced PPI in LE vs. SD rats after ic vehicle infusion. A. Comparable levels of PPI in SD and LE rats one week after surgery, prior to ic infusions. B. Significantly reduced PPI in LE vs. SD rats (#) on the first day of ic testing, in rats from all infusion sites that received vehicle infusions. C. Significantly reduced PPI in unoperated LE vs. SD rats (#) (n = 12/strain) that underwent a “mock-infusion” procedure light restraint in the manner typically used for ic infusions for 60 sec, light pressure to top of head, noises of pumps and timers according to normal ic infusion procedures) prior to startle measures. No strain differences in PPI were detected in a control group (n = 12/strain) taken directly from a sound insulated room and placed into the startle boxes. The startle test session was identical to that used for Experiments 1-3.